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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP4K1 All Species: 1.21
Human Site: T393 Identified Species: 2.42
UniProt: Q92918 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92918 NP_009112.1 833 91296 T393 I P T P A E D T P P P L P P K
Chimpanzee Pan troglodytes XP_522848 845 94894 S421 T I K H C P D S E S R A P Q I
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 N95 Y Y G S Y F K N T D L W I V M
Dog Lupus familis XP_541641 821 90630 P393 P T P A E D T P P P L P P K P
Cat Felis silvestris
Mouse Mus musculus P70218 827 91516 I391 I P A P S E N I P P P L P P K
Rat Rattus norvegicus Q924I2 873 98660 V410 H S T L K A K V P P P L P P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515144 898 100018 V440 R S T L K R A V P P P L P P K
Chicken Gallus gallus Q5ZJK4 486 55318 N94 Y Y G S Y F K N T D L W I V M
Frog Xenopus laevis Q6IP06 493 56486 C101 L W I V M E Y C G A G S V S D
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 Y100 D L W I V M E Y C G A G S V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 E277 V S K C L V K E P D D R A T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23356 1096 122486 G577 D I M M N G E G T L R G P N K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.5 25.2 89.8 N.A. 83 44.6 N.A. 42.4 25.5 24 24.6 N.A. 25.5 N.A. 23.8 N.A.
Protein Similarity: 100 61.8 40 93.4 N.A. 89.8 61.5 N.A. 58.3 39.8 39.8 39.7 N.A. 44 N.A. 40.2 N.A.
P-Site Identity: 100 13.3 0 20 N.A. 73.3 53.3 N.A. 53.3 0 6.6 0 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 20 0 26.6 N.A. 86.6 53.3 N.A. 53.3 0 13.3 6.6 N.A. 13.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 9 9 9 0 0 9 9 9 9 0 9 % A
% Cys: 0 0 0 9 9 0 0 9 9 0 0 0 0 0 0 % C
% Asp: 17 0 0 0 0 9 17 0 0 25 9 0 0 0 9 % D
% Glu: 0 0 0 0 9 25 17 9 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 0 0 9 0 9 9 9 9 17 0 0 0 % G
% His: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 17 9 9 0 0 0 9 0 0 0 0 17 0 9 % I
% Lys: 0 0 17 0 17 0 34 0 0 0 0 0 0 9 42 % K
% Leu: 9 9 0 17 9 0 0 0 0 9 25 34 0 0 0 % L
% Met: 0 0 9 9 9 9 0 0 0 0 0 0 0 0 17 % M
% Asn: 0 0 0 0 9 0 9 17 0 0 0 0 0 9 0 % N
% Pro: 9 17 9 17 0 9 0 9 50 42 34 9 59 34 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 9 0 0 0 0 9 0 0 0 0 17 9 0 0 0 % R
% Ser: 0 25 0 17 9 0 0 9 0 9 0 9 9 9 9 % S
% Thr: 9 9 25 0 0 0 9 9 25 0 0 0 0 9 0 % T
% Val: 9 0 0 9 9 9 0 17 0 0 0 0 9 25 0 % V
% Trp: 0 9 9 0 0 0 0 0 0 0 0 17 0 0 0 % W
% Tyr: 17 17 0 0 17 0 9 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _